Yale-Penn Cohort

Summary

Stub for the Yale-Penn Cohort, a study population used for genetic analyses of substance-use-related traits. Auto-created because it is a stub-eligible Cohort referenced in the Tractor-Mix validation described below; expand when a source describing the cohort's design and recruitment is ingested.

Use in Tractor-Mix Validation

Tractor-Mix was applied to alcohol-related traits in the Yale-Penn Cohort, identifying AFR-ancestry-specific associations for alcohol use disorder (AUD).[1] The paper reports this result only in its Supplementary Information, which was not accessible at ingestion time, so no further quantitative detail is recorded here.

Citations

[1] Tan, T. et al. (2025). Extending Genome-Wide Association Studies to admixed cohorts with high degrees of relatedness. medRxiv preprint. DOI: 10.1101/2025.05.27.25328444. Source: 2025.05.27.25328444v1.full.md. Supports: existence of the Tractor-Mix AUD analysis in this cohort (Results, main text only — Supplementary Figure 10 not inspected).