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Alasoo Lab

Summary

The Alasoo Lab is a research group led by Kaur Alasoo at the University of Tartu's Institute of Computer Science. The lab focuses on functional genomics, statistical genetics, and computational biology, particularly the integration of genome-wide association studies (GWAS) with molecular traits.

Research Focus

  • Functional Genomics and eQTLs: The lab is a key contributor to the development of the eQTL Catalogue, a comprehensive resource of uniformly processed human gene expression and splicing QTLs.
  • Genetic Colocalization: The lab develops software like gpu-coloc to enable high-throughput genetic colocalization across millions of traits.
  • Causal Inference: Utilizing methods like cis-Mendelian Randomization to evaluate potential drug targets and identify causal genes underlying disease risk.

Citations