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Inouye Lab

Summary

The Inouye Lab (Systems Genomics Lab) is led by Michael Inouye and is situated across the Cambridge Baker Systems Genomics Initiative, the Department of Public Health and Primary Care at the University of Cambridge, and the Baker Heart and Diabetes Institute. The lab's research lies at the intersection of genomics, bioinformatics, machine learning, and medicine, with a strong focus on clinical translation and risk prediction.

Research Areas

  • Polygenic Risk Scores (PRS): Development and validation of PRS for cardiovascular and metabolic diseases.
  • Multi-omics Integration: Integrating transcriptomic, proteomic, and metabolomic traits to construct predictive models (such as OmicsPred).
  • Systems Medicine: Leveraging large-scale cohorts such as UK Biobank and INTERVAL to identify early biomarkers and molecular networks associated with health outcomes.

Citations