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Lambert Lab

Summary

The Lambert Lab is led by Samuel A. Lambert and is based at the Department of Public Health and Primary Care, University of Cambridge, and Health Data Research UK (HDRUK) Cambridge. The lab focuses on the standardization, calculation, and evaluation of polygenic scores (PGS) and their integration with multi-omic genetic prediction models.

Key Projects and Contributions

  • PGS Catalog Calculator: Co-development of the pgsc_calc tool for standardized polygenic score computation and ancestry normalization (see PGS Catalog Calculator).
  • OmicsPred: Co-development of OmicsPred as a resource for hosting genetic prediction models of transcriptomic, proteomic, and metabolomic traits.
  • FAIR Data Standards: Advancing guidelines for reporting genetic scores and performance metrics in clinical and research settings.

Citations